NOTE:
this website will soon be replaced by a new github page.
Meanwhile, up-to-date information on adegenet can be found on
github:
https://github.com/thibautjombart/adegenet/wiki
adegenet is an
package dedicated
to the exploratory analysis of genetic data. It implements a set
of tools ranging from multivariate methods to spatial genetics
and genome-wise SNP data analysis.
It is developed on
Github by
Thibaut Jombart,
Zhian N Kamvar, Caitlin Collins, Roman Lustrik,
Marie-Pauline Beugin, Brian Knaus, Peter Solymos, Vladimir Mikryukov, Klaus Schliep,
Ismail Ahmed, Anne Cori, Tobias Erik Reiners, Federico Calboli and Péter Sólymos, and
officially released on CRAN periodically.
adegenet is described in the following publications:
- Jombart T. (2008) adegenet: a R package for the
multivariate analysis of genetic markers. Bioinformatics 24: 1403-1405. doi:
10.1093/bioinformatics/btn129 [link
to a free pdf]
- Jombart T. and Ahmed I. (2011) adegenet 1.3-1: new tools for the analysis
of genome-wide SNP data. Bioinformatics.
doi: 10.1093/bioinformatics/btr521 [link
to
the bublisher's website]
sPCA, DAPC and its
web application, typological coherence of markers,
Monmonier algorithm, ...
The main
features of adegenet are:
- data representation (classes)
suitable for multivariate analysis
- data import
from GENETIX, STRUCTURE, Genepop, Fstat, Easypop, or any
dataframe of genotypes
- data import from aligned
DNA sequences to SNPs
- data import from aligned
protein sequences to polymorphic sites
- data export to
the R packages genetics, hierfstat, LDheatmap
- handling of different
levels of ploidy
- handling of codominant
markers and
presence/absence data
- basic and advanced data
manipulation
- basic data
information (heterozygosity, numbers of alleles,
sample sizes, ...)
- computation of genetic
distances
- simulation of hybridization
- methods for spatial
genetics: sPCA, tests
for global and local structuring, Monmonier algorithm
- the seqTrack
algorithm for reconstructing genealogies of
haplotypes
- simulation of genealogies
of haplotypes
- Discriminant Analysis of Principal Components (DAPC)
- efficient genome-wise SNP data handling and analysis
- extraction of SNPs from genomic alignments
- graph-based
clustering of genomic data
- identification of mutations between pairs of sequences
- visualization of SNPs density and test for the
randomness of their distribution
- web interface for DAPC, including feature
selection and cross validation
- fast maximum-likelihood clustering and identification of hybrids using snapclust
- export multivariate analysis results for geographic mapping using mvmapper
- and more...
Maintainer:
Thibaut Jombart (
website)
Suggestions, comments and contributions are most welcome!